Rosanna Romeo del Castello was born in Catania on 28 August 1946 to Consalvo Romeo del Castello and tennis player Ucci Manzutto.
Graduated in Economics at the University of Catania, for forty years she was a professor of Banking Technology and Economics of Financial Intermediaries at the same university and for four years at the University of Calabria in Cosenza. In addition to being the author of academic publications in the field of ethical finance, she was also co-editor of the book La sfida del vino made in Sicily: strategie di crescita del settore e del Territorio, published in 2005 by Giappichelli Editore of Turin.
He currently manages, together with his daughter, the farm and wine family Fattorie Romeo del Castello, in Contrada Allegracore in Randazzo, on the slopes of Etna.